76% of patients undergoing amputation experience chronic pain.¹
Treatment Challenge
Advanced surgical methods have shown promise, but fail to consistently prevent neuroma formation
When nerves are cut during amputation, they attempt to regenerate. Without a distal nerve to regenerate into, they often develop neuromas, causing phantom and residual limb pain for amputees.
Successful treatment requires:
Protecting transected nerves
Preventing axonal escape
Eliminating neuroma formation
Preventing Neuromas
For amputees, no current treatment optimizes recovery and successfully prevents neuroma formation.
Reducing Pain
Neuromas are the leading cause of pain in amputees and surgeons seek solutions that consistently reduce pain.
SOLUTION
Introducing the first and only fully absorbable in situ forming technology designed to protect transected nerves, prevent axonal escape and eliminate neuroma formation.
Pending FDA Clearance. Not available for sale.
Hydrogel designed to
Optimize Recovery & Prevent Neuroma Formation
Based on allay Nerve Cap mass loss at accelerated degradation (benchtop)²
Tailored absorption
Tulavi’s adaptive hydrogel remains in place during the most critical period of healing and then, through the process of hydrolysis, is fully absorbed in 8 months.
DEMONSTRATED NEUROMA PREVENTION
Across 6 preclinical studies, N>200, no neuroma formation present²
Fast & intuitive procedure
Direct Visualization
Transparent gel enables direct visualization to ensure procedural success.
Fast-Acting
Activates upon delivery to enhance procedural confidence.
Sutureless
Without the need for sutures, procedural time is reduced, and granulomas are prevented.
Mioton LM, et al. Targeted Muscle Reinnervation Improves Residual Limb Pain, Phantom Limb Pain, and Limb Function: A Prospective Study of 33 Major Limb Amputees. Clin Orthop Relat Res. 2020 Sep;478(9):2161-2167.